IQCB1 Antikörper (C-Term)

Produktnummer ABIN2788212

Dieser Anti-IQCB1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von IQCB1 in WB. Geeignet für Human, Maus, Ratte, Hund, Pferd, Kaninchen, Rind (Kuh) und Meerschweinchen.

Kurzübersicht für IQCB1 Antikörper (C-Term) (ABIN2788212)

Target: IQCB1 (IQ Motif Containing B1 (IQCB1))

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Kaninchen, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IQCB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IQCB1 Antikörper

Bindungsspezifität: C-Term

Sequenz: LQHYFMGRAL EERAQQHREA LIAQISTNVE QLMKAPSLKE AEGKEPELFL

Homologie: Cow: 92%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 85%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against IQCB1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human IQCB1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 465 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu IQCB1

Target: IQCB1 (IQ Motif Containing B1 (IQCB1))

Andere Bezeichnung: IQCB1

Hintergrund: This gene encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. The encoded protein has a central coiled-coil region and two calmodulin-binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. The protein is thought to play a role in ciliary function. Defects in this gene result in Senior-Loken syndrome type 5. Alternative splicing results in multiple transcript variants.
Alias Symbols: NPHP5, PIQ, SLSN5
Protein Interaction Partner: TUBB, KRT87P, ATP6V1G2, PRKDC, IGHG1, UBE2V1, HDAC6, ITGA11, TWF2, XPOT, NUDT3, RAB35, CPLX1, CDIPT, TUBB4B, TUBB3, BPNT1, TUBA1B, CALCOCO2, SEC16A, IQCB1, SGPL1, PEA15, DYNLL1, GEMIN2, HIRIP3, TUBA1A, YWHAB, UCHL1, UBB, TUBB2A, TUBA4A, HSP90B1, TPI1, THB
Protein Size: 465

Molekulargewicht: 51 kDa

Gen-ID: 9657

NCBI Accession: NM_001023571, NP_001018865

UniProt: Q3KS09